Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:16 PM
Ignite Modification Date:
2025-12-24 @ 12:16 PM
NCT ID:
NCT06999161
Eligibility Criteria:
Inclusion Criteria:
* Adult patients (≥18 years old)
* Admitted to the intensive care unit for acute brain injury
* Exhibiting Augmented Renal Clearance (ARC), defined by a urinary creatinine clearance (ClCrU) greater than 130 mL/min/1.73 m² on at least one measurement
* Receiving Therapeutic Drug Monitoring (TDM)-guided treatment with one of the following beta-lactam antibiotics: amoxicillin/clavulanic acid, cefotaxime, piperacillin/tazobactam, cefepime, or meropenem
* Affiliated with or benefiting from a health insurance scheme
Exclusion Criteria:
* Estimated life expectancy \<24 hours
* Patients who have expressed opposition to study participation
* Patients under legal protection (guardianship, curatorship, or court protection)
* Patients currently in an exclusion period determined by participation in another study
* Patients already enrolled in a study that precludes concurrent participation in an observational study
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06999161
Study Brief:
Protocol Section:
NCT06999161