Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:48 PM
Ignite Modification Date:
2025-12-24 @ 3:48 PM
NCT ID:
NCT01879592
Eligibility Criteria:
Inclusion Criteria:
* Patients are aged 6 years old up to 21 years old
* Children with sickle cell disease with the genotype SS, SC, or S β 0 thal
* African American children with asthma who do not have sickle cell disease or sickle cell disease trait.
* African American children with no chronic disease
* Physician diagnosed asthma and atopy (of any asthma severity) plus a family history of asthma 89,90
* Patients whose controller respiratory medications and maintenance medications for sickle cell disease (e.g. hydroxyurea) have been unchanged for the previous 4 weeks
Exclusion Criteria:
* Patients who are current smokers
* Patients who had an inflammatory event related to sickle cell disease (pain episode, priapism, acute chest syndrome, urgent medical visit), asthma exacerbation, or respiratory infection within 1 month prior to the blood, saliva, and urine collection.
* Patients who are receiving chronic transfusion therapy and who have received a transfusion within 90 days prior to blood, saliva, and urine collection.
* Patients who have received treatment with a leukotriene synthesis inhibitor or a leukotriene modifier\[montelukast (Singulair®)\] within the 2 weeks prior to blood and urine collection.
* Women who are pregnant or lactating
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
6 Years
Maximum Age:
20 Years
Study:
NCT01879592
Study Brief:
Protocol Section:
NCT01879592