Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:45 PM
Ignite Modification Date:
2025-12-24 @ 3:45 PM
NCT ID:
NCT06278792
Eligibility Criteria:
Inclusion Criteria:
* Older than 18 years
* Provide written informed consent
* Hospital admission with signs and symptoms of congestion warranting intravenous decongestive therapy
* Congestion score of at least 2 based upon the presence of edema, pleural effusion, or ascites
* N-terminal pro-B-type natriuretic peptide (NT-proBNP) level of at least 500 ng per litre (800 ng per litre in case of atrial fibrillation)
Exclusion Criteria:
* Patients unable to collect a 48h-urine collection
* Estimated GFR below 20 ml/min/1.73m\^2
* Concomitant diagnosis of an acute coronary syndrome
* Need for inotropic or vasopressor support
* Ventricular assist device
* Renal replacement therapy
* Treatment with intravenous loop diuretics \> 80mg furosemide or an equivalence of another loop diuretic (40mg furosemide = 1mg bumetanide) during the index hospitalization and prior to randomization
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06278792
Study Brief:
Protocol Section:
NCT06278792