Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:44 PM
Ignite Modification Date:
2025-12-24 @ 3:44 PM
NCT ID:
NCT00805792
Eligibility Criteria:
Inclusion Criteria:
* Definite or probable acute ischemic cerebrovascular syndrome (AICS), as defined by Kidwell et al (Stroke. 2003;34:2995-8).
* Experimental treatment started within 24 hours of onset of symptoms.
* Age ≥ 18 years.
* Ability and willingness to return for follow-up visits.
* Willingness of an available informant who knows the patient well to participate in informant-based questionnaires for the duration of the follow-up period.
* Living in independent or semi-independent living situation before the stroke.
* Fluent in English before the stroke.
* Provides written informed consent.
* Near visual acuity of at least 20/200 in at least one eye.
* Auditory acuity of at least having the ability to detect finger rubbing in at least one ear.
Exclusion Criteria:
* Parkinson's disease or restless leg syndrome.
* Partial or generalized seizures.
* No acute decompensated heart failure
* Routinely requiring daytime supplemental oxygen before the stroke; study participants on continuous positive air pressure (CPAP) for obstructive sleep apnea remain eligible.
* Gastrointestinal or genitourinary surgery within 1 month of screening.
* Gastrointestinal bleeding.
* Syncope or symptomatic bradycardia.
* Creatinine ≥ 3.5 mg/dL or requiring dialysis.
* Peptic ulcer disease.
* Asthma.
* Tracheostomy or endotracheal intubation.
* Taking donepezil or other acetylcholinesterase inhibitor at screening.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00805792
Study Brief:
Protocol Section:
NCT00805792