Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:35 PM
Ignite Modification Date:
2025-12-24 @ 3:35 PM
NCT ID:
NCT00045292
Eligibility Criteria:
DISEASE CHARACTERISTICS:
* Disease requiring one of the following types of stem cell transplantation:
* First myeloablative allogeneic peripheral blood stem cell
* Unrelated cord blood
* Bone marrow
* Related or unrelated donor
* T-cell depleted or non-T-cell depleted
* CD34 selected or non-selected
* Patient must be cytomegalovirus (CMV)-seronegative and donor must be CMV-seropositive
* No transplantation with nonmyeloablative regimens, including any of the following:
* Fludarabine and total body irradiation (TBI) (2 Gy or less)
* TBI alone (2 Gy)
* Fludarabine, cytarabine, and idarubicin
* Fludarabine and melphalan (140 mg/m\^2 or less)
* No definite or probable pre-transplantation diagnosis of invasive mold infection (aspergillosis, fusariosis, or zygomycosis), including pulmonary or hepatic nodules consistent with invasive mold infection for which patients are receiving targeted prophylaxis with amphotericin or other mold-active products
* No pre-transplantation-CMV disease (gastrointestinal or pneumonia)
PATIENT CHARACTERISTICS:
Age
* 12 and over
Performance status
* Not specified
Life expectancy
* Not specified
Hematopoietic
* Not specified
Hepatic
* Not specified
Renal
* Not specified
Other
* HIV negative
* No hypersensitivity to acyclovir or valacyclovir
* Not pregnant
* Fertile patients must use effective contraception
PRIOR CONCURRENT THERAPY:
Biologic therapy
* See Disease Characteristics
Chemotherapy
* See Disease Characteristics
Endocrine therapy
* Not specified
Radiotherapy
* See Disease Characteristics
Surgery
* Not specified
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
12 Years
Study:
NCT00045292
Study Brief:
Protocol Section:
NCT00045292