Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:12 PM
Ignite Modification Date:
2025-12-24 @ 12:12 PM
NCT ID:
NCT02462161
Eligibility Criteria:
Inclusion Criteria:
* Previous or subsequent diagnosis of Alzheimer's disease or mild cognitive impairment
* Ability to communicate in English
Exclusion Criteria:
* Preexisting diabetes
* Clinically significant elevations in liver function test
* Clinically significant elevations in lipid profile
* Prior lumbar lumbar surgeries or other medical conditions that render lumbar punctures unsafe
* Hemoglobin \<8 g/dl
* Significant neurologic disease that might affect cognition, other than Alzheimer's disease, including stroke, Parkinson's disease, multiple sclerosis, or recent severe head injury (within the last year) with loss of consciousness \>30 minutes or with permanent neurologic sequelae
* Significant medical illness or organ failure, such as uncontrolled hypertension or cardiovascular disease, chronic obstructive pulmonary disease, liver disease, or kidney disease
* Current use of antipsychotic, anticonvulsant, anxiolytic, anticoagulant or sedative medications
* Current or previous use of glucose-lowering agents or insulin;
* Chronic use (≥ 3 times per week) of nasal sprays of any type for any indication
* Premenopausal status (defined as having had a period within the last year).
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
89 Years
Study:
NCT02462161
Study Brief:
Protocol Section:
NCT02462161