Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:27 PM
Ignite Modification Date:
2025-12-24 @ 3:27 PM
NCT ID:
NCT00418392
Eligibility Criteria:
Inclusion Criteria:
1. Male or female.
2. Age between 15 and 40 years old.
3. First episode of spontaneous pneumothorax.
4. Symptomatic (dyspnea or chest pain) or the rim of air is \> 2cm on CXR requiring simple aspiration
5. Complete or nearly complete and persistent lung expansion immediately following manual aspiration
6. Organ Function Requirements:
* Adequate hematological function (Hb \> 10 g/dl, ANC \> 1.5 x 109/L, platelets \> 100 x 109/L)
* Normal renal and hepatic functions: serum creatinine \< 1 x ULN, SGPT and SGOT\< 2.5 x ULN, alkaline phosphatase \< 5 x ULN
7. Written inform consent
Exclusion Criteria:
1. With underlying pulmonary disease (asthma, chronic obstructive pulmonary disease, bronchiectasis, etc)
2. With hemothorax or tension pneumothorax requiring chest tube insertion or operation
3. A history of previous pneumothorax
4. A history of previous ipsilateral thoracic operation
5. Allergy to tetracycline or minocycline
6. Pregnant or lactating patients.
7. Other serious concomitant illness or medical conditions:
* Congestive heart failure or unstable angina pectoris.
* History of myocardial infarction within 1 year prior to the study entry.
* Uncontrolled hypertension or arrhythmia.
* History of significant neurologic or psychiatric disorders, including dementia or seizure.
* Active infection requiring i.v. antibiotics.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
15 Years
Maximum Age:
40 Years
Study:
NCT00418392
Study Brief:
Protocol Section:
NCT00418392