Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:20 PM
Ignite Modification Date:
2026-03-26 @ 3:20 PM
NCT ID:
NCT00782327
Eligibility Criteria:
Inclusion Criteria:
* Patients \> 10 years
* Diagnosis of MFS, according to the Ghent criteria and/or genetically proven FBN1 mutations or linkage
* Consent obtained (written) either for the patient and for his/her parents (\<18y
* Z-score of the aorta at the level of the sinus of Valsalva ≥2 (BSA adjusted)
* ARB naïve patients
Exclusion Criteria:
* Poor echocardiographic window,limiting the accurate measurement of the aortic root
* Contra-indication for ARB: Bilateral renal artery stenosis, renal function abnormalities (creatinine above normal for age), hyperkalemia
* Intolerance for ARB (eg angioedema)
* Pregnancy or breast feeding women
* Absence of effective contraception
* Liver function abnormalities
* Heart Failure
* Patients included in other clinical trial
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
10 Years
Study:
NCT00782327
Study Brief:
Protocol Section:
NCT00782327