Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:20 PM
Ignite Modification Date:
2026-03-26 @ 3:20 PM
NCT ID:
NCT07491718
Eligibility Criteria:
Inclusion Criteria:
* Males and females \>18 years of age
* Clinical presentation of takotsubo cardiomyopathy
* Have capacity to give formal consent
Exclusion Criteria:
* Unable to tolerate or contraindication to magnetic resonance imaging
* Renal failure (estimated glomerular filtration rate \<30 mL/min/1.73 m2) - this would be assessed by performing a blood test
* Prior history of cardiomyopathy
* Current pregnancy
* Weight greater than 250kg
* Severe asthma for study 1 (given Bisoprolol is contraindicated in this condition)
* Type 1 diabetes mellitus for study 2 (given Dapaglifozin is contraindicated in this population)
* Significant hypotension (given the medications prescribed as part of the study can also cause hypotension as a side effect)
* Significant bradycardia for study 1 (given Bisoprolol can exacerbate any pre-existing significant bradycardia)
* Prescribed Digoxin (this medication interacts with the Manganese)
* Unable to give formal consent
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07491718
Study Brief:
Protocol Section:
NCT07491718