Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:20 PM
Ignite Modification Date:
2026-03-26 @ 3:20 PM
NCT ID:
NCT07386418
Eligibility Criteria:
Inclusion Criteria:
1. Eligibility for PCI due to angina or angina-equivalent symptoms on exertion
2. 2 severe epicardial stenoses in a major coronary artery, defined as:
1. ≥70% stenosis in a coronary artery with ≥2.5mm diameter, on invasive coronary angiography (ICA)
2. Severe stenosis in a vessel with ≥2.5mm diameter, on CTCA
3. Evidence of ischaemia on an invasive or non-invasive test, including:
1. Physiological test during invasive coronary angiography (ICA)
2. Dobutamine stress echocardiography (DSE)
3. Stress perfusion cardiac magnetic resonance (CMR)
4. Myocardial perfusion scintigraphy (MPS)
5. Fractional flow reserve computed-tomography (FFR-CT)
Exclusion Criteria:
1. Age \<18 years
2. Acute coronary syndrome within 3 months
3. Previous coronary artery bypass graft
4. Significant left main stem disease
5. Single lesion amenable to PCI
6. Chronic total occlusion of the target artery
7. Moderate to severe valve disease
8. LVEF ≤40%, contraindication to PCI or drug-eluting stents
9. PCI performed with drug-eluting balloons without stenting
10. Contraindication to antiplatelet therapy
11. Contraindication to adenosine
12. Physical inability to exercise with an ergometer
13. Femoral artery access
14. Pregnancy
15. Inability to consent
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07386418
Study Brief:
Protocol Section:
NCT07386418