Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:20 PM
Ignite Modification Date:
2026-03-26 @ 3:20 PM
NCT ID:
NCT07383220
Eligibility Criteria:
Inclusion Criteria:
* Age between 50 and 60 years. Both sexes were included Patients had been diagnosed with hypertension for at least 5 years.
Patients had resistant hypertension according to (Whelton et al 2018), defined as:
* Systolic blood pressure (SBP) ≥140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg despite the use of three or more antihypertensive medications of different classes, including a diuretic,
* or controlled blood pressure (\<140/90 mmHg) while on four or more antihypertensive medications.
Body Mass Index (BMI) 25: 34.9 kg/m²
Increased waist circumference, defined as:
* Greater than 102 cm for males.
* Greater than 88 cm for females.
Exclusion Criteria:
* Secondary hypertension due to identifiable causes (e.g., renal artery stenosis, primary aldosteronism, pheochromocytoma).
* History of major cardiovascular events in the last 6 months (e.g., myocardial infarction, stroke, or heart failure exacerbation).
* Severe musculoskeletal or neurological disorders that impair the ability to perform isometric exercise safely (e.g., recent joint replacement, severe osteoarthritis, stroke with residual motor deficit).
* Contraindications to the use of Transcutaneous Electrical Nerve Stimulation (TENS):
Implanted electronic devices: pacemakers, cardioverter defibrillators. Uncontrolled arrhythmias. Sever skin condition: open wounds, rashes, burns, eczema. Peripheral neuropathy or sensory loss.
-Known cognitive impairment or psychiatric conditions that would limit the ability to follow instructions or provide informed consent.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
60 Years
Study:
NCT07383220
Study Brief:
Protocol Section:
NCT07383220