Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:20 PM
Ignite Modification Date:
2026-03-26 @ 3:20 PM
NCT ID:
NCT07306702
Eligibility Criteria:
Inclusion Criteria
* American Society of Anesthesiologists (ASA) physical status II-III
* Male patients aged 65 years or younger
* Undergoing lobectomy for the first time
* High nicotine dependence, confirmed by the Fagerström Test for Nicotine Dependence (FTND) with an FTND score of 6 or higher
* No history of substance abuse and no recent use of analgesic medications (e.g., opioids or non-steroidal anti-inflammatory drugs) prior to surgery
* Able to understand the procedure for patient-controlled intravenous analgesia (PCIA) and able to complete the study assessment scales
Exclusion Criteria
* History of mental illness or cognitive disorder; or currently receiving antidepressant treatment and unable to cooperate with examinations and assessments
* Bradycardia (heart rate 50 beats/min or lower) or second- or third-degree atrioventricular block
* Body mass index (BMI) greater than 30 kg/m²
* Use of analgesics, sedatives, beta-blockers, or alpha-2 agonists prior to surgery
* Required reoperation due to serious postoperative complications (e.g., bleeding)
* Severe cardiovascular, cerebrovascular, hepatic, or renal disease, resulting in inability to remove the endotracheal tube after surgery or inability to use the analgesia pump correctly
* Failure to abstain from smoking for at least 2 weeks prior to surgery
Healthy Volunteers:
False
Sex:
MALE
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT07306702
Study Brief:
Protocol Section:
NCT07306702