Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:19 PM
Ignite Modification Date:
2026-03-26 @ 3:19 PM
NCT ID:
NCT07316933
Eligibility Criteria:
Inclusion Criteria:
* Age between 50 and 85 years
* Diagnosis of severe gonarthrosis according to the clinical and radiographic criteria of the American College of Rheumatology guidelines.
* On the waiting list for unilateral total knee replacement (TKR) surgery
Exclusion Criteria:
* Pain in the contralateral leg with an intensity ≥80/100 mm on the visual analog scale (VAS) during daily activities.
* Previous hip or knee replacement surgery and osteotomy within the last year.
* Autoimmune arthritis
* Medical conditions that contraindicate exercise.
* Participation in exercise programs (\>2 days/week with training at intensities of 10-15 1RM) in the previous six months.
* History of stroke, brain surgery, major depression, or self-reported cognitive impairment that could affect performance in the study.
* Cardiovascular, thrombotic, or vascular risk factors (uncontrolled hypertension, peripheral arterial disease, history of deep vein thrombosis or pulmonary embolism, heart failure, severe varicose veins, or uncontrolled anticoagulant therapy).
* Skin or local alterations at the cuff application site (ulcers, open wounds, infections, lymphedema, or severe edema).
* Inability to communicate normally or with impaired communication skills.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
85 Years
Study:
NCT07316933
Study Brief:
Protocol Section:
NCT07316933