Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:18 PM
Ignite Modification Date:
2026-03-26 @ 3:18 PM
NCT ID:
NCT07344194
Eligibility Criteria:
Inclusion Criteria:
* Male or female participants, aged 18 to 80 years; women of childbearing potential must not be pregnant.
* Diagnosis of Essential Tremor with a score greater than 2 on items 5 or 6 of the Fahn-Tolosa-Marin Tremor Rating Scale despite optimized medical therapy.
* Medication-refractory tremor, defined as prior use of both first-line medications (propranolol and primidone) at maximally tolerated doses without adequate tremor control.
* Ability to provide written informed consent in accordance with institutional policies.
* Ability to comply with all study procedures and follow-up assessments as defined by the study protocol.
Exclusion Criteria:
* Unstable or untreated psychiatric disorders.
* Inability to provide informed consent.
* Uncontrolled medical conditions, including but not limited to uncontrolled diabetes mellitus, hypertension, symptomatic pulmonary disease, or symptomatic cardiac disease.
* Concomitant participation in another investigational drug or device study.
* Pregnancy or breastfeeding.
* Presence of an implanted deep brain stimulation (DBS) system.
* History of epilepsy not adequately controlled, defined as seizure-free for less than 5 years.
* Presence of a cardiac pacemaker.
* Presence of metallic implants in any part of the body that are contraindicated for rTMS.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07344194
Study Brief:
Protocol Section:
NCT07344194