Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:18 PM
Ignite Modification Date:
2026-03-26 @ 3:18 PM
NCT ID:
NCT07491367
Eligibility Criteria:
Inclusion Criteria:
* Kellgren-Lawrence (KL) Grade 1-3 knee osteoarthritis
* Symptoms of knee osteoarthritis for at least 3 months before presentation in one knee
* Will be able to attend and perform physical therapy
Exclusion Criteria:
* Received injection therapy for knee osteoarthritis in the past 6 months
* Have severe arthritis diagnosed in ≥1 major joint by radiology criteria
* History of septic arthritis
* Underwent knee surgery for osteoarthritis or osteochondral defects within 1 year before randomization (e.g., autograft or allograft surgery)
* Have had high tibial osteotomy, partial knee replacement, patellar resurfacing, total knee replacement, or have existing surgical hardware in the knee
* Received a platelet-rich plasma injection elsewhere in the body within the past 3 months
* Have a platelet disorder or bleeding disorder
* Have a rheumatologic disease, autoimmune disorder, immunocompromised status, or active history of cancer
* Are taking chemotherapy, require regular prednisone, or require regular anti-inflammatory use
* Are pregnant, breastfeeding, or unwilling to practice birth control during the study
* If both knees have osteoarthritis and the other knee has KL score equal to or greater than 2.
* Have uncontrolled illness, physical disability, or other contraindication to aerobic exercise training
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07491367
Study Brief:
Protocol Section:
NCT07491367