Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:17 PM
Ignite Modification Date:
2026-03-26 @ 3:17 PM
NCT ID:
NCT07329556
Eligibility Criteria:
Inclusion Criteria:
* Age between 18 and 75 years
* Diagnosis of an inflammatory rheumatic disease (including rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, reactive arthritis, connective tissue diseases, Behçet disease, familial Mediterranean fever, or crystal arthropathies), confirmed by a rheumatologist
* Healthy volunteers without a history of rheumatic or chronic inflammatory disease (for the control group)
* Ability to undergo non-invasive skin autofluorescence measurement
* Ability and willingness to provide written informed consent
Exclusion Criteria:
* Diagnosis of diabetes mellitus (type 1 or type 2)
* Chronic kidney disease with estimated glomerular filtration rate (eGFR) \< 60 mL/min/1.73 m²
* Active malignancy or history of malignancy within the past 5 years
* Presence of acute infection or acute inflammatory condition at the time of assessment
* Secondary causes of systemic inflammation unrelated to the underlying rheumatic disease (e.g., uncontrolled endocrine disorders, chronic liver disease)
* Use of medications known to markedly affect AGE accumulation or skin autofluorescence measurements (e.g., recent high-dose systemic glucocorticoids)
* Pregnancy or breastfeeding
* Presence of significant skin conditions (e.g., extensive dermatitis, scars, tattoos, or burns) at the measurement site that may interfere with skin autofluorescence assessment
* Inability to comply with study procedures or to provide informed consent
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT07329556
Study Brief:
Protocol Section:
NCT07329556