Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:17 PM
Ignite Modification Date:
2026-03-26 @ 3:17 PM
NCT ID:
NCT07486869
Eligibility Criteria:
Inclusion Criteria:
* Progressive interstitial lung disease as determined by at least 2/4 of the following:
1. worsening respiratory symptoms;
2. worsening or new oxygen requirement;
3. worsening disease on CT chest;
4. worsening Forced Vital Capacity (FVC1) or Diffusing Capacity for Carbon Monoxide (DLCO) on pulmonary function tests
* MDA5 antibodies present
* Elevated ferritin above the upper limit of normal (ULN)
* Participant at least 18 years old
Exclusion Criteria:
* Active, untreated bacterial, mycobacterial or fungal infection
* Active herpes zoster infection
* Currently requiring extracorporeal membrane oxygenation (ECMO)
* Participant refusal to participate in the study
* Pregnant women
* Prisoners
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07486869
Study Brief:
Protocol Section:
NCT07486869