Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:17 PM
Ignite Modification Date:
2026-03-26 @ 3:17 PM
NCT ID:
NCT07432035
Eligibility Criteria:
Inclusion Criteria:
* Participants aged 12 years or older at the time of enrollment
* Genetically or clinically confirmed CMT, based on established diagnostic criteria
* Presence of foot deformity and/or gait impairment attributable to CMT, as determined by a treating clinician
* Ability to ambulate at least 10 meters, with or without assistive devices
* Medically eligible for either functional surgical intervention or structured physical therapy, as determined by the treating team
* Willingness and ability to participate in longitudinal follow-up assessments
* Provision of written informed consent
Exclusion Criteria:
* Previous major foot or ankle surgery that substantially altered lower-limb biomechanics
* Presence of non-CMT-related neurological disorders affecting gait (eg, stroke, Parkinson disease, multiple sclerosis)
* Severe musculoskeletal conditions unrelated to CMT that limit walking ability (eg, advanced hip or knee osteoarthritis)
* Active lower-limb infection, ulceration, or acute injury at the time of enrollment
* Severe cognitive impairment or psychiatric condition precluding reliable participation
* Medical contraindications to surgery or exercise-based rehabilitation, when relevant
* Inability to complete baseline functional assessments or anticipated inability to complete follow-up
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
12 Years
Maximum Age:
60 Years
Study:
NCT07432035
Study Brief:
Protocol Section:
NCT07432035