Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:17 PM
Ignite Modification Date:
2026-03-26 @ 3:17 PM
NCT ID:
NCT07424235
Eligibility Criteria:
Inclusion Criteria:
* Male or female patients aged 50 years or older at baseline.
* Diagnosis of geographic atrophy secondary to dry age-related macular degeneration in the study eye.
* Well-demarcated geographic atrophy lesions confirmed by fundus autofluorescence imaging, with a total lesion area between 2.5 mm² and 17.5 mm².
* Presence of hyperautofluorescence in the junctional zone of the geographic atrophy lesion.
* Best-corrected visual acuity between 45 and 83 ETDRS letters at baseline.
* Availability of longitudinal clinical and imaging data with at least 6 months of follow-up.
Exclusion Criteria:
* Evidence or history of neovascular (wet) age-related macular degeneration in the study eye.
* Prior intravitreal therapy or systemic treatments specifically targeting age-related macular degeneration.
* Geographic atrophy lesions contiguous with peripapillary atrophy.
* Coexisting ocular diseases that could independently affect visual acuity or retinal structure.
* Incomplete or poor-quality clinical or imaging data precluding reliable assessment of study outcomes.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Study:
NCT07424235
Study Brief:
Protocol Section:
NCT07424235