Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:17 PM
Ignite Modification Date:
2026-03-26 @ 3:17 PM
NCT ID:
NCT07461532
Eligibility Criteria:
Inclusion Criteria:
1. A clinical, radiological, or histologic diagnosis of cirrhosis of any etiology.
2. Splenomegaly with secondary hypersplenism.
3. Bleeding portal hypertension.
4. No evidence of portal vein thrombosis (PVT) or spleno-mesenteric thrombosis by ultrasound evaluation and angio-CT prior to surgery.
5. Underwent laparoscopic splenectomy and azygoportal disconnection (LSD) at our center.
6. Received routine aspirin anticoagulation (2.5 mg twice daily) immediately after surgery.
7. Had no imaging evidence (Doppler ultrasound or CT) of PVT during postoperative months 6 to 12.
8. Developed de novo PVT after 12 months post-surgery.
9. Provided informed consent to participate in the study.
Exclusion Criteria:
1. Hepatocellular carcinoma or any other malignancy,
2. Hypercoagulable state other than the liver disease related
3. DRUGS- oral contraceptives, anticoagulation or anti-platelet drugs.
4. Child - Pugh C
5. Recent peptic ulcer disease
6. History of Hemorrhagic stroke
7. Pregnancy.
8. Uncontrolled Hypertension
9. Human immunodeficiency virus (HIV) infection
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07461532
Study Brief:
Protocol Section:
NCT07461532