Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:16 PM
Ignite Modification Date:
2026-03-26 @ 3:16 PM
NCT ID:
NCT07419932
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 14 years at enrollment.
* Eastern Cooperative Oncology Group (ECOG) performance status of 0-2.
* Histologically or cytologically confirmed thyroid carcinoma, including differentiated thyroid carcinoma (DTC), medullary thyroid carcinoma (MTC), poorly differentiated thyroid carcinoma (PDTC), and anaplastic thyroid carcinoma (ATC).
* LATC defined as clinical stage T4N0-1 at baseline, as confirmed by a multidisciplinary thyroid oncology board.
* For patients with distant metastasis, the potential benefit from surgical intervention must be documented by the treating team.
* Presence of at least one measurable lesion, according to Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1.
* Normal function of major organs.
* Written informed consent obtained.
Exclusion Criteria:
* Patients who refuse tumor tissue biopsy or surgery.
* Prior thyroid or major neck surgery.
* History of other treatments for cancer, including surgery, chemotherapy, radiotherapy, or molecular targeted therapy, that may affect the current treatment plan.
* Concurrent active malignancies.
* Uncontrolled systemic diseases, including diabetes, hypertension, etc.
* Pregnancy or breastfeeding.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
14 Years
Maximum Age:
80 Years
Study:
NCT07419932
Study Brief:
Protocol Section:
NCT07419932