Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:16 PM
Ignite Modification Date:
2026-03-26 @ 3:16 PM
NCT ID:
NCT07468604
Eligibility Criteria:
Inclusion criteria
1. Age 18 years or older
2. PCC following COVID-19 infection with symptoms lasting for at least three months
3. Ability to read, write, and understand English
4. Quantified autonomic symptoms from at least one domain as reported by the patient on the screener Composite Autonomic Symptom Score (COMPASS-31), i.e. a COMPASS-31 score greater than 0. COMPASS-31 assesses 6 domains of autonomic symptoms: Orthostatic Intolerance, Vasomotor, Secretomotor, Gastrointestinal, Bladder, and Pupillomotor.
5. Patients should be stable on any PCC-related medications for at least four weeks.
Exclusion criteria
1. History of co-existing conditions that are a contraindication for SGBCSBCSB:
1. Unilateral vocal cord paralysis; Severe chronic obstructive pulmonary disease (FEV1 between 30-50% of predicted value)
2. Recent myocardial infarction (within the last one year), Cardiac conduction block of any degree
3. Glaucoma
4. Infection or mass at injection site, bleeding disorders
2. Comorbid conditions that could confound study results, such as:
1. Active autoimmune disorders
2. Pre-existing autonomic dysfunction (e.g. POTS, IST, and CRPS) prior to COVID-19
3. Untreated psychiatric conditions (e.g. severe anxiety or PTSD requiring medication adjustments during the study period)
3. Recent history of major surgery or cerebrovascular events within the last three months
4. Allergy to local anesthetic; Inability to extend the neck for any reason (e.g. severe arthritis)
5. History of prior stellate ganglion block
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07468604
Study Brief:
Protocol Section:
NCT07468604