Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:15 PM
Ignite Modification Date:
2026-03-26 @ 3:15 PM
NCT ID:
NCT07348250
Eligibility Criteria:
Inclusion Criteria:
* Signed informed consent prior to any study procedures
* Women of childbearing potential: abstinent or use 2 contraception methods (one barrier) during study and 90 days post last injection
* Men: use 2 contraception methods and refrain from sperm donation during study and 90 days post last injection
* PD \& HE participants: Age 40-80 years; HP participants: Age 18-50 years
* Adequate circulation and normal clotting for arterial cannulation (if applicable)
* HE participants: no neurological disorder, no first-degree relative with idiopathic PD
* HP participants: healthy with no clinically relevant findings
Exclusion Criteria:
* Unwilling or unable to provide informed consent
* Clinically significant hepatic, renal, cardiovascular, pulmonary, or systemic illness
* Pregnant or breastfeeding
* Contraindication to PET or MRI procedures (e.g., implants, claustrophobia)
* History of severe allergic reactions to PET tracers or related compounds
* Current or prior participation in investigational drug study within 30 days
* Any condition that may interfere with study conduct or participant safety
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT07348250
Study Brief:
Protocol Section:
NCT07348250