Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:15 PM
Ignite Modification Date:
2026-03-26 @ 3:15 PM
NCT ID:
NCT07388966
Eligibility Criteria:
Inclusion Criteria:
1. Aged 3 years old or older at the time of consent.
2. Written informed consent obtained:
1. From the parent(s) or legal guardian(s) for participants under 18 years old.
2. From participants 18 years old and older.
3. Affiliated to, or beneficiary of a social security category
4. Able to walk unassisted for at least 10 meters.
5. Genetically confirmed diagnosis with one pathogenic variant (ACMG class IV \& V) of achondroplasia or hypochondroplasia.
6. Participant (and caregivers for participants under 18 years old) willing and able to comply with all study procedures including: questionnaires, Syde® related procedures
Exclusion Criteria:
1. Subjects who have short stature condition other than ACH/HCH.
2. Presence of cognitive disorders that limit their understanding of the data collection process (training of device use and 4-week recording periods every 6 months, device return at the end of the study), the implication of the study and consent.
3. Presence or history of any concurrent disease or condition that could interfere with study participation, impact pediatric growth, affect motor or balance or gait function (such as neurological, endocrine, infectious, allergic, osteoarthritis, or inflammatory), assessed by the investigator.
4. Females who are pregnant, or planning to become pregnant during the study duration.
5. Body Mass Index = 35 kg/m2.
6. Recent upper and/or lower limbs injury (trauma/fracture or surgery) in the 6 months preceding inclusion.
7. Prior limb lengthening surgery or planned or expected to have limb lengthening surgery while enrolled in the study.
8. Presence of guided growth hardware (such as 8-plates) or planned orthopedic surgeries during the study.
9. Vulnerable patient (guardianship, curatorship or safeguarding of justice), unable to provide informed consent or who is unable to express their consent.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
3 Years
Maximum Age:
65 Years
Study:
NCT07388966
Study Brief:
Protocol Section:
NCT07388966