Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:14 PM
Ignite Modification Date:
2026-03-26 @ 3:14 PM
NCT ID:
NCT07402759
Eligibility Criteria:
Inclusion Criteria Male participants aged 20-50 years
Clinical diagnosis of oligoasthenozoospermia, confirmed by two semen analyses according to WHO 2010/2021 criteria:
Sperm concentration \<15 million/mL, and Progressive motility \<32% Attempting conception with a partner for ≥12 months, or referred for infertility evaluation Willing and able to take oral L-carnitine and comply with all study visits and procedures Able and willing to provide written informed consent, including consent for genetic testing (TDRD9 analysis) Exclusion Criteria Known obstructive azoospermia Grade III varicocele requiring surgical correction, unless repaired ≥6 months prior to enrollment Use of fertility supplements or hormonal therapy within the 3 months prior to enrollment (washout required) Active genitourinary infection (e.g., prostatitis) or systemic illness known to affect fertility Known severe systemic disease, including uncontrolled diabetes mellitus or severe hepatic or renal disease Known hypersensitivity or allergy to L-carnitine History of testicular cancer or receipt of chemotherapy within the past 2 years
Healthy Volunteers:
False
Sex:
MALE
Minimum Age:
20 Years
Maximum Age:
50 Years
Study:
NCT07402759
Study Brief:
Protocol Section:
NCT07402759