Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:14 PM
Ignite Modification Date:
2026-03-26 @ 3:14 PM
NCT ID:
NCT07409259
Eligibility Criteria:
Inclusion Criteria:
* Aged 18 to 65 years, regardless of gender.
* Diagnosed with Acute-on-Chronic Liver Failure (ACLF) according to the diagnostic criteria in the "Guidelines for Diagnosis and Treatment of Liver Failure (2024 Edition)."
* COSSH-ACLF II score \< 7.4.
* Participants must be fully informed about the study and voluntarily sign a written informed consent form prior to participation.
Exclusion Criteria:
* Patients with chronic liver failure.
* Patients with active bleeding or Disseminated Intravascular Coagulation (DIC) that has not been effectively controlled.
* Known allergy to blood products or any medications/drugs used in the treatment protocol.
* Patients with circulatory failure.
* History of myocardial infarction, cerebral infarction, or cerebral hemorrhage within the past 6 months.
* History of malignancy within the past 5 years (excluding cured basal cell carcinoma of the skin or carcinoma in situ of the cervix).
* Pregnant or lactating women.
* Any other conditions that, in the opinion of the investigator, make the patient unsuitable for participation in the trial.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT07409259
Study Brief:
Protocol Section:
NCT07409259