Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:14 PM
Ignite Modification Date:
2026-03-26 @ 3:14 PM
NCT ID:
NCT07395895
Eligibility Criteria:
Inclusion Criteria:
* • Postmenopausal women aged 50-70 years.
* Clinical and radiographic diagnosis of knee osteoarthritis according to the American College of Rheumatology criteria.
* Radiographic severity classified as Kellgren-Lawrence grade II or III.
* Chronic knee pain for a duration of at least 3 months.
* Pain intensity ≥4 on the Visual Analog Scale.
* Ability to ambulate independently with or without assistive devices.
* Ability to understand and follow instructions.
* Willingness to participate and provide written informed consent.
Exclusion Criteria:
* • Severe knee osteoarthritis (Kellgren-Lawrence grade IV).
* History of knee surgery or intra-articular injections within the previous 6 months.
* Presence of inflammatory rheumatic diseases such as rheumatoid arthritis or gout.
* Neurological disorders affecting lower limb function.
* Uncontrolled metabolic, cardiovascular, or systemic diseases.
* Current or recent use of metformin or other antidiabetic medications.
* Skin lesions, infections, or hypersensitivity at the iontophoresis site.
* Contraindications to electrotherapy such as pacemakers or implanted electronic devices.
* Body mass index ≥35 kg/m².
* Participation in another clinical trial within the last 3 months.
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
50 Years
Maximum Age:
70 Years
Study:
NCT07395895
Study Brief:
Protocol Section:
NCT07395895