Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:25 PM
Ignite Modification Date:
2025-12-24 @ 3:25 PM
NCT ID:
NCT02121392
Eligibility Criteria:
Inclusion Criteria:
* end stage degenerative joint disease
* enrolled for unilateral total knee arthroplasty at the University of Chicago
* age \< 85
* ability to understand and willingness to sign a written informed consent
Exclusion Criteria:
* age \> 85
* American Society of Anesthesiologists physical status \> 3
* known hypersensitivity to lidocaine, bupivacaine, ropivacaine or other local anesthetic agents
* Coagulopathy, specifically INR \> 1.5, Platelets \< 100, therapy with clopidogrel within 5 days prior to surgery, enoxaparin or fondaparinux within the last 24 hours prior to surgery, patients with anti-phospholipid syndrome requiring aggressive anticoagulation perioperatively
* History of alcohol or substance abuse (including strong opioids - morphine, oxycodone, methadone, fentanyl, ketobemidone), taking \> 50 mg morphine equivalent daily of opioids
* Pre-existing femoral neuropathy or radiculopathy
* Patients with poor ability to communicate
Healthy Volunteers:
True
Sex:
ALL
Maximum Age:
85 Years
Study:
NCT02121392
Study Brief:
Protocol Section:
NCT02121392