Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:07 PM
Ignite Modification Date:
2025-12-24 @ 3:07 PM
NCT ID:
NCT04999592
Eligibility Criteria:
Inclusion Criteria:
* ≥18 years of age
* Comatose (do not follow simple verbal commands)
* Have any initial heart rhythm (shockable or non-shockable)
* OHCA including the emergency department
Exclusion Criteria:
* Name on opt-out list
* In-hospital cardiac arrest
* Interval \>6 hours from ICU admission to study drug receipt
* Preexisting terminal disease making 180-day survival unlikely
* Refused informed consent
* Emergent coronary artery bypass grafting
* Anaphylaxis or angioedema to beta-lactam antibiotics (i.e., cephalosporins or penicillins)
* Under legal guardianship or prisoner
* Known colonization with methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant enterococcus (VRE)
* Clinical bacterial infection prior to hospital admission defined as any one of the following:
* Infectious prodrome preceding OHCA
* Active course of antibiotics for infection prior to admission
* Active infection documented in the electronic medical record
* Family or surrogate endorsement of an active infection
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04999592
Study Brief:
Protocol Section:
NCT04999592