Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:07 PM
Ignite Modification Date:
2025-12-24 @ 3:07 PM
NCT ID:
NCT01800292
Eligibility Criteria:
Inclusion Criteria:
* Patients with New York Heart Association/World Health Organization(NYHA/WHO)functional class II-III
* Patients with mean pulmonary artery pressure \>25 mmHg, pulmonary capillary wedge pressure \>15 mmHg ≤18, and pulmonary vascular resistance \>3 wood units
* Age \>18 and \<80
* Stable on antihypertensives and diuretics\>3 months
* No evidence of active ischemic heart disease
* 6 minute walk distance \>150 meters and \<450 meters
Exclusion Criteria:
* \- Left ventricular ejection fraction \<50%
* Patients with significant restrictive lung disease (FVC\<60% predicted) and/or significant obstructive lung disease (FEV1 \<55% predicted) within 1 year of enrollment
* Poorly interpretable grey scale echocardiographic images
* Contraindications to right heart catheterization
* Nitroglycerin therapy
* Moderate-severe aortic and mitral valve abnormality
* Contraindications to submaximal exercise testing
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT01800292
Study Brief:
Protocol Section:
NCT01800292