Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:06 PM
Ignite Modification Date:
2025-12-24 @ 3:06 PM
NCT ID:
NCT07150559
Eligibility Criteria:
Inclusion Criteria:
1. Aortic CTA confirmed as ATAAD according to the 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease;
2. Adult patients (18-70 years) weighing 50-120 kg;
3. Time interval between the onset of symptoms and operation is less than 14 days;
4. Indications for total aortic arch replacement are available;
5. Signed informed consent and availability for follow-up.
Exclusion Criteria:
1. History of chronic renal failure, hepatocirrhosis, and hepatic insufficiency;
2. Severe gastrointestinal complications of non-aortic dissection, such as mesenteric ischemia, gastrointestinal bleeding, hepatopancreaticobiliary dysfunction, and intestinal obstruction;
3. History of severe cerebral infarction (with cerebral infarction sequels);
4. Preoperative intubation or unconsciousness;
5. Inflammatory aortic diseases, such as Takayasu arteritis and Behçet's disease, etc;
6. History of infectious aortic diseases;
7. History of cardiac and aortic surgery;
8. History of malignancy or previous radiotherapy;
9. Pregnant or feeding women, or anyone planning to reproduce during the test period;
10. Without an informed consent signature;
11. Participating in any other clinical trial;
12. Having other causes not eligible for operation.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT07150559
Study Brief:
Protocol Section:
NCT07150559