Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:07 PM
Ignite Modification Date:
2025-12-24 @ 12:07 PM
NCT ID:
NCT04140461
Eligibility Criteria:
Inclusion Criteria:
* Confirmed HIV infection
* Naive to antiretroviral therapy
* Cryptococcal antigen, smear or culture positive in cerebrospinal fluid
* Agree to participate the study
Exclusion Criteria:
* Having receiving antifungal treatment for ≥3 days
* ALT or AST \> 5\* upper limit of detection (ULD), or neutrophil\< 0.5\*10E9 cells/L, or hemoglobin \< 90g/L or platelet \<50\*10E9/L or serum creatinine \> ULD
* Pregnancy or breastfeeding
* Concomitant medications that are contraindicated with any research drug
* Any other contraindications for using amphotericin B or 5FC
* Inability to follow-up as accessed by the investigator
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04140461
Study Brief:
Protocol Section:
NCT04140461