Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:55 PM
Ignite Modification Date:
2025-12-24 @ 2:55 PM
NCT ID:
NCT00585559
Eligibility Criteria:
Inclusion Criteria:
* Ages ≥ 20
* Fisher Grade III or III + IV SAH based upon admitting CT scan
* Aneurysm secured by either clipping or coiling within 72 hours of SAH
* Intracranial aneurysm confirmed by angiography or CTA
* Presence of ventriculostomy for external ventricular drainage (EVD) prior to randomization
Exclusion Criteria:
* Consent unobtainable
* Enrollment in another interventional study
* Patient is pregnant or lactating
* Known co-morbidities that could affect outcome of this study
* Contraindication to CTA
* Serum creatinine \> 1.4
* Documented allergy to iodinated contrast that cannot be adequately treated with premedication
* Documented allergy and/or intolerance to ApAP
* Baseline liver disease
* History of recent alcohol abuse with documented ALT or AST above normal laboratory values
* Documented history of both malnutrition and decreased serum albumin below normal lab values
* Documented abnormal platelet count below normal lab values
* Documented abnormal PT or PTT above normal lab values
* History or evidence of active asthma
* Documented allergy and/or intolerance to N-acetylcysteine
* Currently taking phenytoin, carbamazepine, or phenobarbital
* Currently taking isoniazid (INH, Lanzid, Nydrazid)
* Severe life-threatening complications resulting from standard aneurysm treatments that will likely prevent completion of the study
* Patient unsuitable for the study, in the opinion of the investigator(s)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
20 Years
Study:
NCT00585559
Study Brief:
Protocol Section:
NCT00585559