Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 5:11 AM
Ignite Modification Date:
2025-12-25 @ 5:11 AM
NCT ID:
NCT03781427
Eligibility Criteria:
Inclusion Criteria:
1. Symptomatic heart failure due to left ventricular systolic dysfunction (LVEF\<50%)
2. Willing and able to give informed consent
3. CRT-D or CRT-P device in situ (\>6 months)
Exclusion Criteria:
1. Angina pectoris symptoms limiting exercise tolerance
2. Unstable heart failure symptoms (medical therapy changes in last three months)
3. Poor imaging quality (details of patients excluded for this reason will be recorded)
4. Calcium channel blocker use (these depress the force of contraction at all heart rates)
5. Uncontrolled heart rate (either atrial fibrillation or sinus rhythm (\>80bts/min))
6. Co-morbidities significantly affecting exercise or symptoms such as severe chronic airways disease or arthritis
7. Haemodynamically significant aortic stenosis
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03781427
Study Brief:
Protocol Section:
NCT03781427