Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 5:11 AM
Ignite Modification Date:
2025-12-25 @ 5:11 AM
NCT ID:
NCT01470027
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of idiopathic PD according to the United Kingdom Parkinson's Disease Society Brain Bank criteria (UKPDSBB) criteria (only for PD group
* Age 50 to 75 years
* Able to give informed consent for study participation
* Not on any medication for PD (anticholinergic agents allowed)
Exclusion Criteria:
* Unable to give informed consent
* Unable to undergo a brain MRI
* PD duration ≥15 years
* Receiving dopamine receptor blocking agents, including typical neuroleptics, prochlorperazine, and metoclopramide
* Diagnosis of major depression or other axis I psychopathology
* Modified Mini-Mental Status Exam (MMSE) ≤ 24/30
* Diagnosis of chronic or persistent illnesses that could affect oxidative stress status, such as diabetes or congestive heart failure
* Significant concomitant medical disease limiting life expectancy to less than 12 months from study inclusion
* Diagnosis of primary mitochondrial disorder, epilepsy, stroke, multiple sclerosis or other neurodegenerative diseases such as Alzheimer's disease or ALS
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
75 Years
Study:
NCT01470027
Study Brief:
Protocol Section:
NCT01470027