Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:54 PM
Ignite Modification Date:
2025-12-24 @ 2:54 PM
NCT ID:
NCT00046059
Eligibility Criteria:
* INCLUSION CRITERIA:
This study will enroll families with the following characteristics:
1. Families with children, seven through 17 years of age, diagnosed with ADHD (defined as the proband for the study).
2. The probands siblings, either affected with ADHD (concordant) or unaffected (discordant), seven years of age and above, including adult siblings.
3. The parents, both mothers and fathers, of enrolled probands.
4. The study will enroll both male and female probands of any ethnic background and race. The prevalence of ADHD is higher in males than in females, so we would expect to have a higher number of male probands than female probands. Both male and female siblings and male and female parents of probands will be enrolled.
5. Adults who are or may be unable to provide informed consent will be excluded.
6. Probands with one parent affected with ADHD or with neither parent affected with ADHD are eligible. Probands from bilineal families, families with both parents affected with ADHD, will be excluded for statistical reasons.
Additional inclusion criteria for the study include:
1\. Ability to read and understand spoken English, since the questionnaires, scales, and interviews that we have license to use in this study are in English.
EXCLUSION CRITERIA:
Some conditions can confound the diagnosis of ADHD. Probands with the following conditions will be excluded from enrollment or will be withdrawn from the study if the condition is discovered subsequent to enrollment:
* Prematurity
* Neurological conditions
* Cardiac surgery
* Prenatal drug exposure
* Hydrocephaly
* Mental Retardation (IQ\<80)
* Known genetic syndromes
* Known CNS disorders
* Known lead toxicity
* Tourette Disorder
* Obsessive-Compulsive Disorder
* Major Depression on both proband and affected sibling
* Pervasive Developmental Disorder
* Age under 7 years old
* Autism
* Other Psychoses
* Post Traumatic Stress Disorder
* Language Disorder (if known)
* Severe Sensory Impairment (visual and hearing)
Probands with the following conditions may be included, but the conditions will be noted during statistical analysis:
* Oppositional Defiant Disorder
* Conduct Disorder
* Tic Disorder
* Obsessive/Compulsive Symptoms
* Anxiety/Phobias
* Learning Disabilities
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
7 Years
Maximum Age:
110 Years
Study:
NCT00046059
Study Brief:
Protocol Section:
NCT00046059