Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 5:05 AM
Ignite Modification Date:
2025-12-25 @ 5:05 AM
NCT ID:
NCT07226518
Eligibility Criteria:
Inclusion Criteria:
1. Age 18-80 years at time of consent
2. All genders included.
3. Chronic ischemic or hemorrhagic stroke \>=6 months, with limited within-home comfortable walking speed \<= 0.49 m/s and unable to walk independently in community (FAC \<= 3)
4. Able to communicate with investigators, follow 2-step command, and correctly answer consent comprehension questions in English.
5. Currently not participating in treadmill walking exercises or exercises involving weight-bearing activities.
6. Have physicians' approval for exercise and be in a stable medical condition
Exclusion Criteria:
1. Hospitalization for cardiac or pulmonary disease within the past 3 months
2. Have musculoskeletal disorders that prevent the participant from participating in the exercise
3. Blood pressure higher than 200/110 mm Hg
4. Significant ataxia or unilateral spatial neglect (score of 2 on NIH stroke scale item 7 or 11)
5. Reported pain that limits or interferes with activities of daily living and physical activity/exercise
6. Diagnosis of other neurological diseases (multiple sclerosis, Alzheimer's disease, Parkinson's disease)
7. Diagnosis of severe depression (HADS score 15-21)
8. Unable to speak or understand English, and travel to the research laboratory.
9. Contraindications to tSCS and TMS
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT07226518
Study Brief:
Protocol Section:
NCT07226518