Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 5:05 AM
Ignite Modification Date:
2025-12-25 @ 5:05 AM
NCT ID:
NCT07132918
Eligibility Criteria:
Inclusion Criteria:
* Age \> 18 years at the time of consent.
* Dosimetric eligibility criteria met using endpoints from QUANTEC (\>10% of heart receives \> 25 Gy) as determined through rapid auto-planning
* Participants with histologically or cytologically proven AJCC, 8th edition including:
* Stage IIIA,IIIB, or IIIC non-operable non-small cell lung cancer
* Stage I-III N0-2 disease esophageal/esophagogastric cancer
* Stage II or III thymoma/thymic carcinoma
* Other cancers in the thoracic region that meet the dosimetric and other clinical trial criteria.
* Participants must have a definitive course of daily fractionated RT planned of at least 15 treatment fractions, typically ranging from 1.8 to 4 Gy/fraction
Exclusion Criteria:
* Definitive clinical or radiologic evidence of metastatic disease with life expectancy \<12 months
* Prior thoracic radiotherapy significantly overlapping the heart region
* Contraindications to MRI
* Severe, active co-morbidity defined as follows: New York Heart Association Functional Classification III/IV are not eligible.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07132918
Study Brief:
Protocol Section:
NCT07132918