Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:53 PM
Ignite Modification Date:
2025-12-24 @ 2:53 PM
NCT ID:
NCT01453959
Eligibility Criteria:
Inclusion Criteria:
* Age 40 to 65 years
* Both sexes and all ethnicities;
* Body Mass Index (BMI) between 20 and 30 kg/m2;
* Patients with hypertension with systolic blood pressure (SBP) between 140 and 159 mmHg and diastolic blood pressure (DBP) between 90 mm Hg and 99 mm Hg, without medication or after four weeks of placebo
Exclusion Criteria:
* Moderate/severe hypertension (BP ≥ 160/100 mm Hg) or secondary cause of hypertension;
* Use of more than two antihypertensive classes at the time of selection;
* Presence of diabetes mellitus or other endocrine disorders;
* Presence of renal impairment (creatinine clearance \<60 ml / min, calculated by Cockcroft-Gault formula);
* Presence of heart failure;
* Presence of cardiac arrhythmias;
* History of stroke, coronary heart disease (myocardial infarction, angina) and peripheral vascular insufficiency;
* Presence of liver failure;
* Alcoholism;
* Psychiatric disorders;
* Use of anovulatory or continuous use of other drugs, such as hormonal or nonhormonal anti-inflammatory drugs that may interfere with blood pressure.
* Pregnant women
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Maximum Age:
65 Years
Study:
NCT01453959
Study Brief:
Protocol Section:
NCT01453959