Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:59 AM
Ignite Modification Date:
2025-12-25 @ 4:59 AM
NCT ID:
NCT02914418
Eligibility Criteria:
Inclusion Criteria:
* Aged 18-70 years old inclusive
* Traumatic and non-traumatic tetraplegic patient following chronic incomplete (AIS C or D) SCI injury (sustained at least three months ago)
* Referred to the Sheffield Spinal Injuries Centre
* Be able to provide written informed consent or verbal consent in the presence of an independent witness
* Spasticity affecting upper limbs with a Modified Ashworth scale (MAS) 2 or above
* Stable medical treatment for at least 1 week before and 1 week after TMS application
* Stable medical condition
Exclusion Criteria:
* Aged less than 18 years old
* Lack the mental capacity to consent
* Ventilated patients with sedation
* Very acute (\<3 months) SCI patients
* Implanted electrical devices such as pacemakers, Concomitant neurological conditions, including any history of epilepsy
* Significant joint-related limitation of passive range of movement
* Unable to attend all TMS sessions
* Pregnancy
* Inability to tolerate TBS
* Significant upper limb contractures
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT02914418
Study Brief:
Protocol Section:
NCT02914418