Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:53 PM
Ignite Modification Date:
2025-12-24 @ 2:53 PM
NCT ID:
NCT02777359
Eligibility Criteria:
Inclusion Criteria:
* migraine headaches with or without aura,migraine onset before age 50
* \>3 migraine attacks or 5 migraine days per month
* failed ≥2 commonly accepted migraine medications:β-receptor blockers, calcium-ion antagonists, antidepressants and non-steroid anti-inflammatory drugs (NSAID).
* PFO documented by TTE or TEE
* PFO meet one of the following conditions:RLS in rest documented by cTTE or cTCD,combine with ASA,the primary patition mobility≥6.5mm,the diameter of PFO≥4mm, combine with Eustachian Valve or Chiari net.
* age 18-60
* else:independent in daily activities,to comply with complete follow-up experiment design
Exclusion Criteria:
* contraindication to antiplatelet or anticoagulant
* inferior vena cava or pelvic vein thrombogenesis leading to complete obstruction,systemic or local infection,septicemia,heart lumen thrombosis
* pregnancy
* combine with pulmonary hypertension or PFO made for a particular channel
* severe allergy to nickel
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT02777359
Study Brief:
Protocol Section:
NCT02777359