Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:53 PM
Ignite Modification Date:
2025-12-24 @ 2:53 PM
NCT ID:
NCT00192959
Eligibility Criteria:
Inclusion Criteria:
* Male or female subjects ≥ 60 years of age.
* American Soc. of Anaesthesiologists Physical Status Classification (ASA) I-III status \[27\]
* Referred for elective orthopaedic knee surgery with an anticipated duration of \> 45 min
* Expected to remain in hospital for at least 3 days
* Expected to be able to comply with the study protocol throughout the study period
* Mini Mental State Examination (MMSE) score \> 23
* Informed consent given
Exclusion Criteria:
* Disease of the CNS (infectious, metabolic, tumours, dementia, epilepsy, major psychiatric disease, confusion/ delirium according to Diagnostic \& Statistical Manual of Mental Disorders (DSM) IV criteria)
* Contradiction for spinal anaesthesia
* Contradiction for laryngeal mask
* Regular use of tranquillisers, or antidepressants, if prescribed by psychiatrist for psychosis or depression
* Undergone neuropsychological testing within the last year
* Unable to follow study procedures, illiteracy, or poor comprehension of the language used in the psychometric tests
* Severe visual or auditory disorder
* Alcoholism or drug abuse
CNS disease BMI \> 35 Inab
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
60 Years
Study:
NCT00192959
Study Brief:
Protocol Section:
NCT00192959