Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:58 AM
Ignite Modification Date:
2025-12-25 @ 4:58 AM
NCT ID:
NCT02482818
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of non-asthmatic chronic cough defined as a cough experienced for a period of at least 8 weeks
* Negative methacholine challenge (within past year)
* Chest x-ray with absence of gross abnormality that could justify the cough or be a cause for the cough (within past 6 months)
* Male or female 18 years or older
* Willing and able to limit to 1 or less alcohol beverage per day (example: 360 ml of beer or 330 ml of cooler or 120 ml of wine)
Exclusion Criteria:
* Concurrent use of Gabapentin or Pregabalin for other indications (seizure disorder, chronic pain)
* History of allergy / intolerance or adverse effect with Gabapentin or Pregabalin.
* Concurrent use of central nervous system depressants (i.e. opioids or benzodiazepines)
* Not able to limit daily alcohol intake as recommended in the inclusion criteria
* Creatinine clearance \< 60ml/min within past three months
* Current Smoker or has been quit less than 8 weeks
* Symptoms of post nasal drip
* History of gastroesophageal reflux. Only participants with untreated Gastroesophageal Reflux Disease (GERD) or less than 8 weeks of therapy will be excluded.
* Symptoms of upper airway cough syndrome
* ACE inhibitor use
* Allergy to citric acid
* Pregnant or nursing women
* History of angioedema or congestive heart failure
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
84 Years
Study:
NCT02482818
Study Brief:
Protocol Section:
NCT02482818