Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:57 AM
Ignite Modification Date:
2025-12-25 @ 4:57 AM
NCT ID:
NCT07144618
Eligibility Criteria:
Inclusion Criteria
1. Able to comprehend and willing to participate in this clinical trial, with signed informed consent.
2. Underwent an abdominal computed tomography (CT) scan within three months prior to surgical treatment, with a non-contrast-enhanced single-slice image at the third lumbar vertebral level available for body composition analysis.
3. Histologically or cytologically confirmed diagnosis of endometrial cancer or ovarian cancer.
4. Age between 20 and 80 years.
5. Good performance status (ECOG performance status of 0, 1, or 2).
6. Adequate hematologic parameters:
* Hemoglobin ≥10 g/dL
* White blood cell count ≥3,000/μL
* Neutrophil count ≥1,500/μL
* Platelet count ≥100,000/μL
7. Adequate organ function:
* Total bilirubin ≤1.5 times the upper limit of normal (ULN).
* Alanine aminotransferase (ALT) / Aspartate aminotransferase (AST) ≤2.5 times ULN (≤5.0 times ULN for patients with liver metastases).
* Creatinine ≤ ULN. Exclusion Criteria
1\. Presence of other major diseases that may be exacerbated by chemotherapy (e.g., autoimmune diseases).
2\. History of other malignancies within the past two years before trial enrollment, except for adequately treated non-melanoma skin cancer, stage 0 cervical carcinoma, or ductal carcinoma in situ of the breast.
3\. Requirement for concurrent treatment of unrelated diseases during the trial period, including chemotherapy, radiotherapy, or investigational drugs.
4\. Mental status deemed unsuitable for participation in the clinical trial. 5. Expected survival time of less than six months. 6. Poor-quality abdominal CT images, clearly attributable to the following causes:
* Motion artifacts due to poor patient compliance.
* Noticeable scoliosis or kyphosis.
* Multiple lumbar vertebral compression fractures.
* Significant generalized edema.
* Presence of metallic implants in the lumbar spine or abdomen.
* Abdominal stoma or significant abdominal wall defects.
* Marked asymmetry or localized atrophy/deficiency of the core abdominal musculature.
Healthy Volunteers:
True
Sex:
FEMALE
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT07144618
Study Brief:
Protocol Section:
NCT07144618