Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:56 AM
Ignite Modification Date:
2025-12-25 @ 4:56 AM
NCT ID:
NCT03807518
Eligibility Criteria:
Inclusion Criteria:
* Be 18 years of age or above;
* Have confirmed Multi Disciplinary Team (MDT) evidence of adenocarcinoma or squamous cell cancer of the oesophagus, oesophago- gastric junction or stomach requiring neoadjuvant therapy and planned curative resection.
* Be referred by a multidisciplinary team meeting for neo adjuvant chemotherapy or neo adjuvant chemoradiotherapy prior to planned oesophagectomy or gastrectomy.
* Have measurement confirming (endoscopic or otherwise) that the tumour starts more than 5cm below cricopharyngeus;
* Be fit for pre-operative anaesthesia and surgery
* Be able to provide written informed consent.
Exclusion Criteria:
* Inability to participate in the exercise program (unable to perform 6 Minute Walk Test, unable to attend for assessment of parameters at any time point).
* Patients with high grade dysplasia (squamous cell or adenocarcinoma);
* Patients who have or develop metastatic disease at time of enrolment or during their neoadjuvant therapy;
* Patients being referred for primary surgery without requirement for neoadjuvant treatment;
* Patients with squamous cell cancer of the oesophagus who the MDT recommends or who individually elect to undergo definitive chemoradiotherapy;
* Evidence of previous/concomitant malignancy that would interfere with this treatment protocol;
* Pregnancy;
* Patients participating in other trials that would interfere with the implementation of this protocol at a particular site.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03807518
Study Brief:
Protocol Section:
NCT03807518