Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:51 AM
Ignite Modification Date:
2025-12-25 @ 4:51 AM
NCT ID:
NCT04972318
Eligibility Criteria:
Inclusion Criteria:
* Patients with community acquired pneumonia requiring invasive mechanical ventilation
* Bilateral pulmonary infiltrates on chest imaging not fully explained by fluid overload in the opinion of the attending physician
* One of the criteria below:
* Oxygen inspired fraction above 50% with a positive end-expiratory pressure of at least 8 cmH2O to main peripheral oxygen saturation above 93%, OR
* Arterial partial pressure of oxygen divided by inspired fraction of oxygen lower than 200 with PEEP values of at least 5 cmH2O
Exclusion Criteria:
* Patients with inclusion criteria for more than 36 hours
* Refusal of the patient´s legal representative
* Acute neurologic disease (stroke, brain trauma, or any disease that may cause intracranial hypertension)
* Patients with current airway fistula or barotrauma
* Patients on chronic home use of oxygen due to underlying lung disease
* Patients younger than 18 years
* Patients not on full code status
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04972318
Study Brief:
Protocol Section:
NCT04972318