Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:51 AM
Ignite Modification Date:
2025-12-25 @ 4:51 AM
NCT ID:
NCT06221618
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 60 years
* All patients had original ultrasound images of bilateral carotid arteries with DICOM format and arteriosclerosis clinical and laboratory data
* Original data of CCTA or examination results in the baseline status are needed for CHD patients
* Original data of intracranial artery MRA or examination results in the baseline status are needed for patients with ischemic stroke.
Exclusion Criteria:
* Age is \<60 years old
* Severe cardiac insufficiency, New York Heart Association(NYHA) class IV and (or) left ventricular ejection fraction \<30%
* Uncontrollable severe hypertension (systolic blood pressure≥ 180 mmHg or diastolic blood pressure≥ 110 mmHg) or uncontrollable severe diabetes mellitus, i.e., diabetes mellitus complicated with acute complications (including diabetic ketoacidosis and hypertonic hyperglycemic nonketosis coma), or acute hyperglycemic state (random blood glucose\> 16.7mmol/L and (or) blood ketone 1.0-3.0mmol/L) without acute complications
* Severe valvular disease (moderate regurgitation and / or stenosis in each valve)
* Various cardiomyopathy caused by hypertrophic cardiomyopathy, dilated cardiomyopathy, alcoholic cardiomyopathy, myocardial amyloidosis
* Severe arrhythmia: persistent atrial fibrillation or atrial flutter, degree II 2 and above atrioventricular block, complete left bundle branch block
* Severe hepatic and renal insufficiency (glutamate transaminase and / or glutamine transaminase\> 3 times the upper limit of normal value, Blood creatinine\> 134 μmol/L or an estimated glomerular filtration rate of \<60ml/min/1.73m2)
* Severe chronic obstructive pulmonary disease or asthma
* Severe non-cardiovascular disease (malignant tumor, thyroid disease, infection, connective tissue disease)
* Mental retardation or mental disorders
* Life expectancy \<3 years due to various factors
* Refusal to sign informed consent
* Allergy to contrast agent should also be ruled out for patients undergoing CCTA for CHD.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
60 Years
Study:
NCT06221618
Study Brief:
Protocol Section:
NCT06221618