Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:48 AM
Ignite Modification Date:
2025-12-25 @ 4:48 AM
NCT ID:
NCT05444218
Eligibility Criteria:
Inclusion Criteria:
* 18-70 years of age;
* in general good health,
* at least one dental implant in function for at least one year with untreated peri-implantitis defined as: presence of bleeding and/or suppuration on gentle probing, probing depths (PD) ≥ 6mm, and bone levels ≥3mm apical of the most coronal portion of the intraosseous part of the implant.
Exclusion Criteria:
* subjects with ≥6 sites with PD ≥5mm;
* individuals that received periodontal treatment within three months prior to entering the study;
* inability to perform proper supramucosal and supragingival plaque control (e.g., due to improper restoration design or lack of skills);
* poorly adapted implant-supported restoration;
* diabetes;
* pregnancy;
* nursing;
* history of allergies to metronidazole and/or amoxicillin, or any other ingredient of oral care products;
* alcohol or drug abuse;
* any systemic diseases that could affect post-operative healing or that required antibiotic premedication for routine dental therapy;
* long-term use of mouthrinses;
* anti-inflammatory medications;
* any other drug that could interfere with the study outcomes within three months prior to entering the study;
* use of antibiotics within six months prior to entering the study.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT05444218
Study Brief:
Protocol Section:
NCT05444218