Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:47 AM
Ignite Modification Date:
2025-12-25 @ 4:47 AM
NCT ID:
NCT01398618
Eligibility Criteria:
Inclusion Criteria:
* household contact of patients with newly diagnosed, culture-confirmed pulmonary tuberculosis
* age \> 18
* tuberculin skin testing-positive or QuantiFERON-positive
* hemoglobin \> 8 g/dL
* neutrophil \> 750 /uL
* total bilirubin \< 2.5 mg/dL
* aspartic and alanine transaminases \< 2 times of upper limit of normal
* willing to receive serology tests for HBV and HCV infection
* no history of allergy to isoniazid and rifampin
* not currently pregnant or breast-feeding
Exclusion Criteria:
* the M. tuberculosis isolate of the index case were isoniazid- or rifampin-resistant
* liver cirrhosis
* clinical or radiographical evidence of active tuberculosis
* active hepatitis
* currently receiving medication that have documented drug interaction with isoniazid or rifampin
* life expectancy \< 3 years
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01398618
Study Brief:
Protocol Section:
NCT01398618