Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 4:41 AM
Ignite Modification Date:
2025-12-25 @ 4:41 AM
NCT ID:
NCT01195818
Eligibility Criteria:
Inclusion Criteria:
* Homozygous sickle cell disease
* \> 18 years
* Patient with social insurance
* Albuminuria/ urinary creatinin \> 10 mg/mmol creatinin (at 2 different times) and MDRD \> 140 ml/min/1.73m2.
* Written inform consent
Exclusion Criteria:
* Hemoglobin SC or S-betathalassemia disease
* Patient currently treated with: lithium, aspirin, antihypertensive drugs, non steroid-antiinflammatory drugs.
* Pregnancy
* Woman without contraception
* Transfusion within the last 3 months
* Intolerance to RAS inhibitors
* Treatment with RAS in the last month
* Patient with Congenital galactosemia or a malabsorption of glucose or lactase deficiency
* Treatment with hydroxyurea began or changed in the last 3 months
* Infection with HIV or C hepatitis
* Angio-edema
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01195818
Study Brief:
Protocol Section:
NCT01195818